Expansion of melanoma-specific lymphocytes in alternate gamma chain cytokines: gene expression variances between T cells and T cell subsets exposed to IL-2 versus IL-7/15

We have previously demonstrated that expansion of activated tumor-sensitized T cells in interleukin (IL)-7/15 results in greater expansion and anti-tumor activity than expansion in IL-2. We sought to determine whether T cells exposed to IL-2 versus IL-7/15 exhibited distinct gene expression patterns...

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Detalles Bibliográficos
Autores principales: Zoon, Christine K., Seitelman, Eric, Keller, Sara, Graham, Laura, Blevins, Tana L., Dumur, Catherine I., Bear, Harry D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205215/
https://www.ncbi.nlm.nih.gov/pubmed/25236493
http://dx.doi.org/10.1038/cgt.2014.48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205215/
https://www.ncbi.nlm.nih.gov/pubmed/25236493
http://dx.doi.org/10.1038/cgt.2014.48

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