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Expansion of melanoma-specific lymphocytes in alternate gamma chain cytokines: gene expression variances between T cells and T cell subsets exposed to IL-2 versus IL-7/15
We have previously demonstrated that expansion of activated tumor-sensitized T cells in interleukin (IL)-7/15 results in greater expansion and anti-tumor activity than expansion in IL-2. We sought to determine whether T cells exposed to IL-2 versus IL-7/15 exhibited distinct gene expression patterns...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205215/ https://www.ncbi.nlm.nih.gov/pubmed/25236493 http://dx.doi.org/10.1038/cgt.2014.48 |