Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma

MIR-491 is commonly co-deleted with its adjacent CDKN2A on chromosome 9p21.3 in glioblastoma (GBM). However, it is not known whether deletion of MIR-491 is only a passenger event or plays an important role. Small-RNA sequencing of samples from GBM patients demonstrated that both mature products of M...

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Detalles Bibliográficos
Autores principales: Li, Xia, Liu, Yuexin, Granberg, Kirsi J., Wang, Qinhao, Moore, Lynette M., Ji, Ping, Gumin, Joy, Sulman, Erik P., Calin, George A., Haapasalo, Hannu, Nykter, Matti, Shmulevich, Ilya, Fuller, Gregory N., Lang, Frederick F., Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205227/
https://www.ncbi.nlm.nih.gov/pubmed/24747968
http://dx.doi.org/10.1038/onc.2014.98

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205227/
https://www.ncbi.nlm.nih.gov/pubmed/24747968
http://dx.doi.org/10.1038/onc.2014.98

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