Thromboembolic Event Detected by Diffusion Weighted Magnetic Resonance Imaging After Coil Embolization of Cerebral Aneurysms

OBJECTIVE: The purpose of this study was to evaluate the occurrence rate of diffusion positive lesions (DPLs), and to assess the peri-procedural risk factors for the occurrence of DPLs in patients who underwent coil embolization of cerebral aneurysms. MATERIALS AND METHODS: A total of 304 saccular a...

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Autores principales: Seo, Dong-Ho, Yoon, Seok-Mann, Park, Hye-Ran, Shim, Jai-Joon, Bae, Hack-Gun, Yun, Il-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cerebrovascular Surgeons; Society of Korean Endovascular Neurosurgeons 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205242/
https://www.ncbi.nlm.nih.gov/pubmed/25340018
http://dx.doi.org/10.7461/jcen.2014.16.3.175
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author Seo, Dong-Ho
Yoon, Seok-Mann
Park, Hye-Ran
Shim, Jai-Joon
Bae, Hack-Gun
Yun, Il-Gyu
author_facet Seo, Dong-Ho
Yoon, Seok-Mann
Park, Hye-Ran
Shim, Jai-Joon
Bae, Hack-Gun
Yun, Il-Gyu
author_sort Seo, Dong-Ho
collection PubMed
description OBJECTIVE: The purpose of this study was to evaluate the occurrence rate of diffusion positive lesions (DPLs), and to assess the peri-procedural risk factors for the occurrence of DPLs in patients who underwent coil embolization of cerebral aneurysms. MATERIALS AND METHODS: A total of 304 saccular aneurysms were embolized during a seven-year period from Jan 2007 to Dec 2013. Of these, postoperative diffusion-weighted images were obtained in 186 procedures. There were 100 ruptured aneurysm and 86 unruptured aneurysms. The coiling procedures were as follows: simple coiling in 96, balloon assisted coiling (BAC) in 39, and stent assisted coiling (SAC) in 51 aneurysms. Clinical, angiographic and procedural factors were analyzed in relation to the occurrence of DPLs. RESULTS: Overall, DPLs were observed in 50.5%. In unruptured aneurysms, DPLs occurred in 23.5% of BAC, 41.9% of SAC and 57.7% of simple coiling (p = 0.08). Among ruptured aneurysms, DPLs occurred in 63.6% of BAC, 62.5% of SAC and 54.3% of simple coiling (p = 0.71). DPLs had a tendency to increase in ruptured aneurysms compared with unruptured aneurysms (57% vs. 43%, p = 0.077). Logistic regression analysis revealed that age > 55 years was the only independent risk factor for the occurrence of DPLs. CONCLUSION: DPLs occured more frequently in ruptured aneurysm and at an older age. Although most DPLs are asymptomatic, careful manipulation of cerebral or extracerebral arteries using various endovascular devices is important to reducing the occurrence of DPLs. BAC appeared to reduce occurrence of TE events in patient with unruptured aneurysm.
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spelling pubmed-42052422014-10-22 Thromboembolic Event Detected by Diffusion Weighted Magnetic Resonance Imaging After Coil Embolization of Cerebral Aneurysms Seo, Dong-Ho Yoon, Seok-Mann Park, Hye-Ran Shim, Jai-Joon Bae, Hack-Gun Yun, Il-Gyu J Cerebrovasc Endovasc Neurosurg Original Article OBJECTIVE: The purpose of this study was to evaluate the occurrence rate of diffusion positive lesions (DPLs), and to assess the peri-procedural risk factors for the occurrence of DPLs in patients who underwent coil embolization of cerebral aneurysms. MATERIALS AND METHODS: A total of 304 saccular aneurysms were embolized during a seven-year period from Jan 2007 to Dec 2013. Of these, postoperative diffusion-weighted images were obtained in 186 procedures. There were 100 ruptured aneurysm and 86 unruptured aneurysms. The coiling procedures were as follows: simple coiling in 96, balloon assisted coiling (BAC) in 39, and stent assisted coiling (SAC) in 51 aneurysms. Clinical, angiographic and procedural factors were analyzed in relation to the occurrence of DPLs. RESULTS: Overall, DPLs were observed in 50.5%. In unruptured aneurysms, DPLs occurred in 23.5% of BAC, 41.9% of SAC and 57.7% of simple coiling (p = 0.08). Among ruptured aneurysms, DPLs occurred in 63.6% of BAC, 62.5% of SAC and 54.3% of simple coiling (p = 0.71). DPLs had a tendency to increase in ruptured aneurysms compared with unruptured aneurysms (57% vs. 43%, p = 0.077). Logistic regression analysis revealed that age > 55 years was the only independent risk factor for the occurrence of DPLs. CONCLUSION: DPLs occured more frequently in ruptured aneurysm and at an older age. Although most DPLs are asymptomatic, careful manipulation of cerebral or extracerebral arteries using various endovascular devices is important to reducing the occurrence of DPLs. BAC appeared to reduce occurrence of TE events in patient with unruptured aneurysm. Korean Society of Cerebrovascular Surgeons; Society of Korean Endovascular Neurosurgeons 2014-09 2014-09-30 /pmc/articles/PMC4205242/ /pubmed/25340018 http://dx.doi.org/10.7461/jcen.2014.16.3.175 Text en © 2014 Journal of Cerebrovascular and Endovascular Neurosurgery http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Seo, Dong-Ho
Yoon, Seok-Mann
Park, Hye-Ran
Shim, Jai-Joon
Bae, Hack-Gun
Yun, Il-Gyu
Thromboembolic Event Detected by Diffusion Weighted Magnetic Resonance Imaging After Coil Embolization of Cerebral Aneurysms
title Thromboembolic Event Detected by Diffusion Weighted Magnetic Resonance Imaging After Coil Embolization of Cerebral Aneurysms
title_full Thromboembolic Event Detected by Diffusion Weighted Magnetic Resonance Imaging After Coil Embolization of Cerebral Aneurysms
title_fullStr Thromboembolic Event Detected by Diffusion Weighted Magnetic Resonance Imaging After Coil Embolization of Cerebral Aneurysms
title_full_unstemmed Thromboembolic Event Detected by Diffusion Weighted Magnetic Resonance Imaging After Coil Embolization of Cerebral Aneurysms
title_short Thromboembolic Event Detected by Diffusion Weighted Magnetic Resonance Imaging After Coil Embolization of Cerebral Aneurysms
title_sort thromboembolic event detected by diffusion weighted magnetic resonance imaging after coil embolization of cerebral aneurysms
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205242/
https://www.ncbi.nlm.nih.gov/pubmed/25340018
http://dx.doi.org/10.7461/jcen.2014.16.3.175
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