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Enhanced production of L-sorbose from D-sorbitol by improving the mRNA abundance of sorbitol dehydrogenase in Gluconobacter oxydans WSH-003

BACKGROUND: Production of L-sorbose from D-sorbitol by Gluconobacter oxydans is the first step to produce L-ascorbic acid on industrial scale. The sldhAB gene, which encodes the sorbitol dehydrogenase (SLDH), was overexpressed in an industrial strain G. oxydans WSH-003 with a strong promoter, P(tufB...

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Detalles Bibliográficos
Autores principales: Xu, Sha, Wang, Xiaobei, Du, Guocheng, Zhou, Jingwen, Chen, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205284/
https://www.ncbi.nlm.nih.gov/pubmed/25323199
http://dx.doi.org/10.1186/s12934-014-0146-8