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Endothelial dysfunction and renal fibrosis in endotoxemia-induced oliguric kidney injury: possible role of LPS-binding protein

INTRODUCTION: The pathophysiology of endotoxemia-induced acute kidney injury (AKI) is characterized by an intense activation of the host immune system and renal resident cells by lipopolysaccharide (LPS) and derived proinflammatory products. However, the occurrence of renal fibrosis in this setting...

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Detalles Bibliográficos
Autores principales: Castellano, Giuseppe, Stasi, Alessandra, Intini, Angelica, Gigante, Margherita, Di Palma, Anna Maria, Divella, Chiara, Netti, Giuseppe Stefano, Prattichizzo, Clelia, Pontrelli, Paola, Crovace, Antonio, Staffieri, Francesco, Fiaccadori, Enrico, Brienza, Nicola, Grandaliano, Giuseppe, Pertosa, Giovanni, Gesualdo, Loreto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205288/
https://www.ncbi.nlm.nih.gov/pubmed/25261195
http://dx.doi.org/10.1186/s13054-014-0520-2