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DNA Hypomethylation-Mediated Overexpression of Carbonic Anhydrase 9 Induces an Aggressive Phenotype in Ovarian Cancer Cells

PURPOSE: Both genetic and epigenetic alterations can lead to abnormal expression of metastasis-regulating genes in tumor cells. Recent studies suggest that aberrant epigenetic alterations, followed by differential gene expression, leads to an aggressive cancer cell phenotype. We examined epigenetica...

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Detalles Bibliográficos
Autores principales: Sung, Hye Youn, Ju, Woong, Ahn, Jung-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205708/
https://www.ncbi.nlm.nih.gov/pubmed/25323905
http://dx.doi.org/10.3349/ymj.2014.55.6.1656