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Spatial memory deficits in a mouse model of late-onset Alzheimer’s disease are caused by zinc supplementation and correlate with amyloid-beta levels

Much of the research in Alzheimer’s disease (AD) that uses mouse models focuses on the early-onset form of the disease, which accounts for less than 5% of cases. In contrast, this study used a late-onset AD model to examine the interaction between increased dietary zinc (Zn) and the apolipoprotein E...

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Detalles Bibliográficos
Autores principales: Flinn, Jane M., Bozzelli, P. Lorenzo, Adlard, Paul A., Railey, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205817/
https://www.ncbi.nlm.nih.gov/pubmed/25374537
http://dx.doi.org/10.3389/fnagi.2014.00174