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Novel Adeno-associated Viruses Derived From Pig Tissues Transduce Most Major Organs in Mice

Recently, development of Adeno-associated virus (AAV) vectors has been focusing on expanding the genetic diversity of vectors from existing sequences via directed evolution or epitope remapping. Apart from intelligent design, AAV isolation from natural sources remains an important source of new AAVs...

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Detalles Bibliográficos
Autores principales: Bello, Alexander, Chand, Allan, Aviles, Jenna, Soule, Geoff, Auricchio, Alberto, Kobinger, Gary P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205840/
https://www.ncbi.nlm.nih.gov/pubmed/25335510
http://dx.doi.org/10.1038/srep06644