Cargando…

sPLA2 IB induces human podocyte apoptosis via the M-type phospholipase A2 receptor

The M-type phospholipase A2 receptor (PLA2R) is expressed in podocytes in human glomeruli. Group IB secretory phospholipase A2 (sPLA2 IB), which is one of the ligands of the PLA2R, is more highly expressed in chronic renal failure patients than in controls. However, the roles of the PLA2R and sPLA2...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Yangbin, Wan, Jianxin, Liu, Yipeng, Yang, Qian, Liang, Wei, Singhal, Pravin C., Saleem, Moin A., Ding, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205892/
https://www.ncbi.nlm.nih.gov/pubmed/25335547
http://dx.doi.org/10.1038/srep06660