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sPLA2 IB induces human podocyte apoptosis via the M-type phospholipase A2 receptor
The M-type phospholipase A2 receptor (PLA2R) is expressed in podocytes in human glomeruli. Group IB secretory phospholipase A2 (sPLA2 IB), which is one of the ligands of the PLA2R, is more highly expressed in chronic renal failure patients than in controls. However, the roles of the PLA2R and sPLA2...
Autores principales: | Pan, Yangbin, Wan, Jianxin, Liu, Yipeng, Yang, Qian, Liang, Wei, Singhal, Pravin C., Saleem, Moin A., Ding, Guohua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205892/ https://www.ncbi.nlm.nih.gov/pubmed/25335547 http://dx.doi.org/10.1038/srep06660 |
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