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Transcriptome analysis of CNS immediately before and after the detection of PrP(Sc) in SSBP/1 sheep scrapie

Sheep scrapie is a transmissible spongiform encephalopathy (TSE), progressive and fatal neurodegenerative diseases of the central nervous system (CNS) linked to the accumulation of misfolded prion protein, PrP(Sc). New Zealand Cheviot sheep, homozygous for the VRQ genotype of the PRNP gene are most...

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Detalles Bibliográficos
Autores principales: Gossner, Anton G., Hopkins, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific Pub. Co 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206282/
https://www.ncbi.nlm.nih.gov/pubmed/25183238
http://dx.doi.org/10.1016/j.vetmic.2014.07.026