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Transcriptome analysis of CNS immediately before and after the detection of PrP(Sc) in SSBP/1 sheep scrapie
Sheep scrapie is a transmissible spongiform encephalopathy (TSE), progressive and fatal neurodegenerative diseases of the central nervous system (CNS) linked to the accumulation of misfolded prion protein, PrP(Sc). New Zealand Cheviot sheep, homozygous for the VRQ genotype of the PRNP gene are most...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Scientific Pub. Co
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206282/ https://www.ncbi.nlm.nih.gov/pubmed/25183238 http://dx.doi.org/10.1016/j.vetmic.2014.07.026 |