Quantitative Cross-Species Extrapolation between Humans and Fish: The Case of the Anti-Depressant Fluoxetine

Fish are an important model for the pharmacological and toxicological characterization of human pharmaceuticals in drug discovery, drug safety assessment and environmental toxicology. However, do fish respond to pharmaceuticals as humans do? To address this question, we provide a novel quantitative...

Descripción completa

Detalles Bibliográficos
Autores principales: Margiotta-Casaluci, Luigi, Owen, Stewart F., Cumming, Rob I., de Polo, Anna, Winter, Matthew J., Panter, Grace H., Rand-Weaver, Mariann, Sumpter, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206295/
https://www.ncbi.nlm.nih.gov/pubmed/25338069
http://dx.doi.org/10.1371/journal.pone.0110467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206295/
https://www.ncbi.nlm.nih.gov/pubmed/25338069
http://dx.doi.org/10.1371/journal.pone.0110467

Ejemplares similares