The effect of clozapine on mRNA expression for genes encoding G protein-coupled receptors and the protein components of clathrin-mediated endocytosis

OBJECTIVES: Clathrin-mediated endocytosis (CME) is an intracellular trafficking mechanism for packaging cargo, including G protein-coupled receptors (GPCRs), into clathrin-coated vesicles (CCVs). The antipsychotic chlorpromazine inhibits CCV assembly of adaptor protein AP2 whereas clozapine increase...

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Detalles Bibliográficos
Autores principales: Sharp, Sally I., Hu, Ying, Weymer, Jon F., Rizig, Mie, McQuillin, Andrew, Hunt, Stephen P., Gurling, Hugh M.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206381/
https://www.ncbi.nlm.nih.gov/pubmed/23811784
http://dx.doi.org/10.1097/YPG.0b013e32835fe51d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206381/
https://www.ncbi.nlm.nih.gov/pubmed/23811784
http://dx.doi.org/10.1097/YPG.0b013e32835fe51d

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