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Cross-linked polyethylenimine–tripolyphosphate nanoparticles for gene delivery
The high transfection efficiency of polyethylenimine (PEI) makes it an attractive potential nonviral genetic vector for gene delivery and therapy. However, the highly positive charge of PEI leads to cytotoxicity and limits its application. To reduce the cytotoxicity of PEI, we prepared anion-enriche...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206394/ https://www.ncbi.nlm.nih.gov/pubmed/25342902 http://dx.doi.org/10.2147/IJN.S61910 |