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Cross-linked polyethylenimine–tripolyphosphate nanoparticles for gene delivery

The high transfection efficiency of polyethylenimine (PEI) makes it an attractive potential nonviral genetic vector for gene delivery and therapy. However, the highly positive charge of PEI leads to cytotoxicity and limits its application. To reduce the cytotoxicity of PEI, we prepared anion-enriche...

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Detalles Bibliográficos
Autores principales: Huang, Xianzhang, Shen, Sujing, Zhang, Zhanfeng, Zhuang, Junhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206394/
https://www.ncbi.nlm.nih.gov/pubmed/25342902
http://dx.doi.org/10.2147/IJN.S61910