mTORC1 Signaling in Oocytes Is Dispensable for the Survival of Primordial Follicles and for Female Fertility

The molecular mechanisms underlying reproductive aging and menopausal age in female mammals are poorly understood. Mechanistic target of rapamycin complex 1 (mTORC1) is a central controller of cell growth and proliferation. To determine whether mTORC1 signaling in oocytes plays a direct role in phys...

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Detalles Bibliográficos
Autores principales: Gorre, Nagaraju, Adhikari, Deepak, Lindkvist, Rebecca, Brännström, Mats, Liu, Kui, Shen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206408/
https://www.ncbi.nlm.nih.gov/pubmed/25338086
http://dx.doi.org/10.1371/journal.pone.0110491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206408/
https://www.ncbi.nlm.nih.gov/pubmed/25338086
http://dx.doi.org/10.1371/journal.pone.0110491

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