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Can Evidence from Genome-Wide Association Studies and Positive Natural Selection Surveys Be Used to Evaluate the Thrifty Gene Hypothesis in East Asians?

Body fat deposition and distribution differ between East Asians and Europeans, and for the same level of obesity, East Asians are at higher risks of Type 2 diabetes (T2D) and other metabolic disorders. This observation has prompted the reclassifications of body mass index thresholds for the definiti...

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Detalles Bibliográficos
Autores principales: Koh, Xuan-Han, Liu, Xuanyao, Teo, Yik-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206456/
https://www.ncbi.nlm.nih.gov/pubmed/25337808
http://dx.doi.org/10.1371/journal.pone.0110974