Perforin Competent CD8 T Cells Are Sufficient to Cause Immune-Mediated Blood-Brain Barrier Disruption

Numerous neurological disorders are characterized by central nervous system (CNS) vascular permeability. However, the underlying contribution of inflammatory-derived factors leading to pathology associated with blood-brain barrier (BBB) disruption remains poorly understood. In order to address this,...

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Detalles Bibliográficos
Autores principales: Johnson, Holly L., Willenbring, Robin C., Jin, Fang, Manhart, Whitney A., LaFrance, Stephanie J., Pirko, Istvan, Johnson, Aaron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206459/
https://www.ncbi.nlm.nih.gov/pubmed/25337791
http://dx.doi.org/10.1371/journal.pone.0111401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206459/
https://www.ncbi.nlm.nih.gov/pubmed/25337791
http://dx.doi.org/10.1371/journal.pone.0111401

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