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Perforin Competent CD8 T Cells Are Sufficient to Cause Immune-Mediated Blood-Brain Barrier Disruption
Numerous neurological disorders are characterized by central nervous system (CNS) vascular permeability. However, the underlying contribution of inflammatory-derived factors leading to pathology associated with blood-brain barrier (BBB) disruption remains poorly understood. In order to address this,...
Autores principales: | Johnson, Holly L., Willenbring, Robin C., Jin, Fang, Manhart, Whitney A., LaFrance, Stephanie J., Pirko, Istvan, Johnson, Aaron J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206459/ https://www.ncbi.nlm.nih.gov/pubmed/25337791 http://dx.doi.org/10.1371/journal.pone.0111401 |
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