Analysis of Gene Expression in Induced Pluripotent Stem Cell-Derived Human Neurons Exposed to Botulinum Neurotoxin A Subtype 1 and a Type A Atoxic Derivative

Botulinum neurotoxin type A1 (BoNT/A1) is a potent protein toxin responsible for the potentially fatal human illness botulism. Notwithstanding, the long-lasting flaccid muscle paralysis caused by BoNT/A has led to its utility as a powerful and versatile bio-pharmaceutical. The flaccid paralysis is d...

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Detalles Bibliográficos
Autores principales: Scherf, Jacob M., Hu, Xiaoyang Serene, Tepp, William H., Ichtchenko, Konstantin, Johnson, Eric A., Pellett, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206481/
https://www.ncbi.nlm.nih.gov/pubmed/25337697
http://dx.doi.org/10.1371/journal.pone.0111238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206481/
https://www.ncbi.nlm.nih.gov/pubmed/25337697
http://dx.doi.org/10.1371/journal.pone.0111238

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