Lack of Renoprotective Effect of Chronic Intravenous Angiotensin-(1-7) or Angiotensin-(2-10) in a Rat Model of Focal Segmental Glomerulosclerosis

Unopposed angiotensin (Ang) II-mediated cellular effects may lead to progressive glomerulosclerosis. While Ang-II can be locally generated in the kidneys, we previously showed that glomerular podocytes primarily convert Ang-I, the precursor of Ang-II, to Ang-(1-7) and Ang-(2-10), peptides that have...

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Detalles Bibliográficos
Autores principales: Velez, Juan Carlos Q., Janech, Michael G., Hicks, Megan P., Morinelli, Thomas A., Rodgers, Jessalyn, Self, Sally E., Arthur, John M., Fitzgibbon, Wayne R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206519/
https://www.ncbi.nlm.nih.gov/pubmed/25337950
http://dx.doi.org/10.1371/journal.pone.0110083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206519/
https://www.ncbi.nlm.nih.gov/pubmed/25337950
http://dx.doi.org/10.1371/journal.pone.0110083

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