Evidence of complex formation between FADD and c-FLIP death effector domains for the death inducing signaling complex

Adaptor protein FADD forms the death inducing signaling complex (DISC) by recruiting the initiating caspases-8 and -10 through homotypic death effector domain (DED) interactions. Cellular FLICE-inhibitory protein (c-FLIP) is an inhibitor of death ligand-induced apoptosis downstream of death receptor...

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Detalles Bibliográficos
Autores principales: Hwang, Eun Young, Jeong, Mi Suk, Park, So Young, Jang, Se Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206723/
https://www.ncbi.nlm.nih.gov/pubmed/24355299
http://dx.doi.org/10.5483/BMBRep.2014.47.9.239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206723/
https://www.ncbi.nlm.nih.gov/pubmed/24355299
http://dx.doi.org/10.5483/BMBRep.2014.47.9.239

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