Cargando…

Evidence of complex formation between FADD and c-FLIP death effector domains for the death inducing signaling complex

Adaptor protein FADD forms the death inducing signaling complex (DISC) by recruiting the initiating caspases-8 and -10 through homotypic death effector domain (DED) interactions. Cellular FLICE-inhibitory protein (c-FLIP) is an inhibitor of death ligand-induced apoptosis downstream of death receptor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hwang, Eun Young, Jeong, Mi Suk, Park, So Young, Jang, Se Bok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206723/ https://www.ncbi.nlm.nih.gov/pubmed/24355299 http://dx.doi.org/10.5483/BMBRep.2014.47.9.239

Ejemplares similares

DED Interaction of FADD and Caspase-8 in the Induction of Apoptotic Cell Death
por: Park, Young-Hoon, et al.
Publicado: (2022)

The Fas–FADD death domain complex structure reveals the basis of DISC assembly and disease mutations
por: Wang, Liwei, et al.
Publicado: (2010)

The Fas/FADD death domain complex structure unravels signaling by receptor clustering
por: Scott, Fiona L., et al.
Publicado: (2008)

Engineered FADD Induces Apoptosis via an Artificial Death-Inducing Signaling Complex (DISC)
por: Suzuki, Emiko, et al.
Publicado: (2009)

Topology is the Principal Determinant in the Folding of a Complex All-alpha Greek Key Death Domain from Human FADD
por: Steward, Annette, et al.
Publicado: (2009)

DED or alive: assembly and regulation of the death effector domain complexes
por: Riley, J S, et al.
Publicado: (2015)

Knock down of Fas-Associated Protein with Death Domain (FADD) Sensitizes Osteosarcoma to TNFα-induced Cell Death
por: Hollomon, Mario G., et al.
Publicado: (2020)

Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer
por: Ray, Pallab, et al.
Publicado: (2016)

Novel Compound Heterozygote Variations in FADD Identified to Cause FAS-Associated Protein with Death Domain Deficiency
por: Kohn, Lisa A., et al.
Publicado: (2020)

Actinomycin D Induces Hepatocyte Cell Death and Upregulation of FADD/MORT1
por: Kim, Peter K.M., et al.
Publicado: (2001)

Differential affinity of FLIP and procaspase 8 for FADD’s DED binding surfaces regulates DISC assembly
por: Majkut, J, et al.
Publicado: (2014)

Redundant and receptor-specific activities of TRADD, RIPK1 and FADD in death receptor signaling
por: Füllsack, Simone, et al.
Publicado: (2019)

Structural insights of homotypic interaction domains in the ligand-receptor signal transduction of tumor necrosis factor (TNF)
por: Park, Young-Hoon, et al.
Publicado: (2016)

NFκB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP
por: Kreuz, Sebastian, et al.
Publicado: (2004)

FADD regulates NF-κB activation and promotes ubiquitination of cFLIP(L) to induce apoptosis
por: Ranjan, Kishu, et al.
Publicado: (2016)

Base Flipping in Open Complex Formation at Bacterial Promoters
por: Karpen, Mary E., et al.
Publicado: (2015)

Activation of FADD-Dependent Neuronal Death Pathways as a Predictor of Pathogenicity for LRRK2 Mutations
por: Melachroinou, Katerina, et al.
Publicado: (2016)

MiR-7a is an important mediator in Fas-associated protein with death domain (FADD)-regulated expression of focal adhesion kinase (FAK)
por: Liu, Yingting, et al.
Publicado: (2016)

The Death Effector Domains of Caspase-8 Induce Terminal Differentiation
por: Mielgo, Ainhoa, et al.
Publicado: (2009)

FADD adaptor in cancer
por: Tourneur, Léa, et al.
Publicado: (2005)

Inhibition of Fas-Associated Death Domain-Containing Protein (FADD) Protects against Myocardial Ischemia/Reperfusion Injury in a Heart Failure Mouse Model
por: Fan, Qian, et al.
Publicado: (2013)

Fas-associated protein with death domain (FADD) regulates autophagy through promoting the expression of Ras homolog enriched in brain (Rheb) in human breast adenocarcinoma cells
por: He, Liangqiang, et al.
Publicado: (2016)

cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms
por: Feoktistova, Maria, et al.
Publicado: (2011)

Flipping the dogma – phosphatidylserine in non-apoptotic cell death
por: Shlomovitz, Inbar, et al.
Publicado: (2019)

Complex Dynamics of Osteoclast Formation and Death in Long-Term Cultures
por: Akchurin, Timur, et al.
Publicado: (2008)

A motif within the armadillo repeat of Parkinson’s-linked LRRK2 interacts with FADD to hijack the extrinsic death pathway
por: Antoniou, Nasia, et al.
Publicado: (2018)

N-Terminal and C-Terminal Domains of Calmodulin Mediate FADD and TRADD Interaction
por: Papoff, Giuliana, et al.
Publicado: (2015)

Efficient recruitment of c‐FLIP(L) to the death‐inducing signaling complex leads to Fas resistance in natural killer‐cell lymphoma
por: Masuda, Azuchi, et al.
Publicado: (2020)

Prognostic significance of TMEM16A, PPFIA1, and FADD expression in invasive ductal carcinoma of the breast
por: Choi, Eun Ji, et al.
Publicado: (2014)

FADD the bad in head and neck cancer
por: Dent, Paul
Publicado: (2013)

The Golgi complex in stress and death
por: Machamer, Carolyn E.
Publicado: (2015)

A Novel Lactate Dehydrogenase Inhibitor, 1-(Phenylseleno)-4-(Trifluoromethyl) Benzene, Suppresses Tumor Growth through Apoptotic Cell Death
por: Kim, Eun-Yeong, et al.
Publicado: (2019)

P45 Forms a Complex with FADD and Promotes Neuronal Cell Survival Following Spinal Cord Injury
por: Sung, Tsung-Chang, et al.
Publicado: (2013)

ATRX/EZH2 complex epigenetically regulates FADD/PARP1 axis, contributing to TMZ resistance in glioma
por: Han, Bo, et al.
Publicado: (2020)

NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells
por: Ruggeri, P, et al.
Publicado: (2016)

Diversity and complexity of cell death: a historical review
por: Park, Wonyoung, et al.
Publicado: (2023)

The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Domain in Catalytic Mechanisms
por: Yan, Mengrong, et al.
Publicado: (2023)

Modulation of the extrinsic cell death signaling pathway by viral Flip induces acute-death mediated liver failure
por: Bittel, Miriam, et al.
Publicado: (2019)

The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth
por: Kim, Hyunjoo, et al.
Publicado: (2014)

Experimental Evidence of Amplitude Death and Phase-Flip Bifurcation between In-Phase and Anti-Phase Synchronization
por: Manoj, Krishna, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3a51u5883jbj3c0smarkucl29d