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Impaired Endothelium-Mesenchymal Stem Cells Cross-talk in Systemic Sclerosis: a Link Between Vascular and Fibrotic Features

INTRODUCTION: To assess if an impaired cross-talk between endothelial cells (ECs) and perivascular/multipotent mesenchymal stem cells (MSCs) might induce a perturbation of vascular repair and leading to a phenotypic switch of MSC toward myofibroblast in Systemic Sclerosis (SSc). METHODS: We investig...

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Detalles Bibliográficos
Autores principales: Cipriani, Paola, Di Benedetto, Paola, Ruscitti, Piero, Campese, Antonio Francesco, Liakouli, Vasiliki, Carubbi, Francesco, Pantano, Ilenia, Berardicurt, Onorina, Screpanti, Isabella, Giacomelli, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206764/
https://www.ncbi.nlm.nih.gov/pubmed/25248297
http://dx.doi.org/10.1186/s13075-014-0442-z