Cargando…

Invariant natural killer T cells regulate anti-tumor immunity by controlling the population of dendritic cells in tumor and draining lymph nodes

BACKGROUND: Invariant natural killer T (iNKT) cells are CD1d-restricted T cells, which respond rapidly to antigen recognition and promote development of anti-tumor immunity in many tumor models. Surprisingly, we previously found that mice deficient in iNKT cells developed spontaneous CD8(+) T cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Pilones, Karsten A, Aryankalayil, Joseph, Babb, James S, Demaria, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206765/
https://www.ncbi.nlm.nih.gov/pubmed/25349699
http://dx.doi.org/10.1186/s40425-014-0037-x