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Invariant natural killer T cells regulate anti-tumor immunity by controlling the population of dendritic cells in tumor and draining lymph nodes

BACKGROUND: Invariant natural killer T (iNKT) cells are CD1d-restricted T cells, which respond rapidly to antigen recognition and promote development of anti-tumor immunity in many tumor models. Surprisingly, we previously found that mice deficient in iNKT cells developed spontaneous CD8(+) T cells...

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Detalles Bibliográficos
Autores principales:	Pilones, Karsten A, Aryankalayil, Joseph, Babb, James S, Demaria, Sandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206765/ https://www.ncbi.nlm.nih.gov/pubmed/25349699 http://dx.doi.org/10.1186/s40425-014-0037-x

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