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Evaluation of ultrahigh-performance liquid chromatography columns for the analysis of unmodified and antisense oligonucleotides

Ultrahigh-performance liquid chromatography has been used for the separation and analysis of unmodified and modified antisense oligonucleotides. For this reason, we tested various columns of low particle sizes in our analysis of unmodified and phosphorothioate oligonucleotides. The influence of both...

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Detalles Bibliográficos
Autores principales: Studzińska, Sylwia, Buszewski, Bogusław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206774/
https://www.ncbi.nlm.nih.gov/pubmed/24939137
http://dx.doi.org/10.1007/s00216-014-7959-5