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Lipid rafts: linking prion protein to zinc transport and amyloid-β toxicity in Alzheimer's disease

Dysregulation of neuronal zinc homeostasis plays a major role in many processes related to brain aging and neurodegenerative diseases, including Alzheimer's disease (AD). Yet, despite the critical role of zinc in neuronal function, the cellular mechanisms underpinning its homeostatic control ar...

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Detalles Bibliográficos
Autores principales: Watt, Nicole T., Griffiths, Heledd H., Hooper, Nigel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206978/
https://www.ncbi.nlm.nih.gov/pubmed/25364748
http://dx.doi.org/10.3389/fcell.2014.00041