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Prion protein and aging

The cellular prion protein (PrP(C)) has been widely investigated ever since its conformational isoform, the prion (or PrP(Sc)), was identified as the etiological agent of prion disorders. The high homology shared by the PrP(C)-encoding gene among mammals, its high turnover rate and expression in eve...

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Detalles Bibliográficos
Autores principales: Gasperini, Lisa, Legname, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207048/
https://www.ncbi.nlm.nih.gov/pubmed/25364751
http://dx.doi.org/10.3389/fcell.2014.00044