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Pathological Role for Exocytotic Glutamate Release from Astrocytes in Hepatic Encephalopathy

Liver failure can lead to generalized hyperammonemia, which is thought to be the underlying cause of hepatic encephalopathy. This neuropsychiatric syndrome is accompanied by functional changes of astrocytes. These glial cells enter ammonia-induced self-amplifying cycle characterized by brain oedema,...

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Detalles Bibliográficos
Autores principales: Montana, Vedrana, Verkhratsky, Alexei, Parpura, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207072/
https://www.ncbi.nlm.nih.gov/pubmed/25342940
http://dx.doi.org/10.2174/1570159X12666140903094700