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Pathological Role for Exocytotic Glutamate Release from Astrocytes in Hepatic Encephalopathy
Liver failure can lead to generalized hyperammonemia, which is thought to be the underlying cause of hepatic encephalopathy. This neuropsychiatric syndrome is accompanied by functional changes of astrocytes. These glial cells enter ammonia-induced self-amplifying cycle characterized by brain oedema,...
Autores principales: | Montana, Vedrana, Verkhratsky, Alexei, Parpura, Vladimir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207072/ https://www.ncbi.nlm.nih.gov/pubmed/25342940 http://dx.doi.org/10.2174/1570159X12666140903094700 |
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