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Fluoxetine and all other SSRIs are 5-HT2B Agonists - Importance for their Therapeutic Effects

Fluoxetine and other serotonin-specific re-uptake inhibitors (SSRIs) are generally thought to owe their therapeutic potency to inhibition of the serotonin transporter (SERT). However, research in our laboratory showed that it affects, with relatively high affinity the 5-HT(2B) receptor in cultured a...

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Detalles Bibliográficos
Autores principales: Peng, Liang, Gu, Li, Li, Baoman, Hertz, Leif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207076/
https://www.ncbi.nlm.nih.gov/pubmed/25342944
http://dx.doi.org/10.2174/1570159X12666140828221720