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New covalent modifications of phosphatidylethanolamine by alkanals: mass spectrometry based structural characterization and biological effects
The pathophysiology of numerous human disorders, such as atherosclerosis, diabetes, obesity and Alzheimer's disease, is accompanied by increased production of reactive oxygen species (ROS). ROS can oxidatively damage nearly all biomolecules, including lipids, proteins and nucleic acids. In part...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207196/ https://www.ncbi.nlm.nih.gov/pubmed/25044840 http://dx.doi.org/10.1002/jms.3373 |