Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis

Aberrant activation of the transcription factor GLI1, a central effector of the Hedgehog (HH) pathway, is associated with several malignancies, including pancreatic ductal adenocarcinoma (PDAC), one of most deadly human cancers. GLI1 has been described as an oncogene in PDAC, making it a promising t...

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Detalles Bibliográficos
Autores principales: Hogenson, Tara L., Lauth, Matthias, Pasca diMagliano, Marina, Fernandez-Zapico, Martin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207242/
https://www.ncbi.nlm.nih.gov/pubmed/25352983
http://dx.doi.org/10.12688/f1000research.5324.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207242/
https://www.ncbi.nlm.nih.gov/pubmed/25352983
http://dx.doi.org/10.12688/f1000research.5324.2

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