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Monitoring drug promiscuity over time

Drug promiscuity and polypharmacology are much discussed topics in pharmaceutical research. Experimentally, promiscuity can be studied by profiling of compounds on arrays of targets. Computationally, promiscuity rates can be estimated by mining of compound activity data. In this study, we have asses...

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Detalles Bibliográficos
Autores principales: Hu, Ye, Bajorath, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207249/
https://www.ncbi.nlm.nih.gov/pubmed/25352982
http://dx.doi.org/10.12688/f1000research.5250.2