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Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model

BACKGROUND: The liver has a crucial role in metabolic homeostasis as well as being the principal detoxification centre of the body, removing xenobiotics and waste products which could potentially include some nanomaterials (NM). With the ever increasing public and occupational exposure associated wi...

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Detalles Bibliográficos
Autores principales: Kermanizadeh, Ali, Løhr, Mille, Roursgaard, Martin, Messner, Simon, Gunness, Patrina, Kelm, Jens M, Møller, Peter, Stone, Vicki, Loft, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207326/
https://www.ncbi.nlm.nih.gov/pubmed/25326698
http://dx.doi.org/10.1186/s12989-014-0056-2