Cargando…
Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model
BACKGROUND: The liver has a crucial role in metabolic homeostasis as well as being the principal detoxification centre of the body, removing xenobiotics and waste products which could potentially include some nanomaterials (NM). With the ever increasing public and occupational exposure associated wi...
Autores principales: | Kermanizadeh, Ali, Løhr, Mille, Roursgaard, Martin, Messner, Simon, Gunness, Patrina, Kelm, Jens M, Møller, Peter, Stone, Vicki, Loft, Steffen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207326/ https://www.ncbi.nlm.nih.gov/pubmed/25326698 http://dx.doi.org/10.1186/s12989-014-0056-2 |
Ejemplares similares
-
Hepatic toxicity assessment of cationic liposome exposure in healthy and chronic alcohol fed mice
por: Kermanizadeh, Ali, et al.
Publicado: (2017) -
Hepatic Oxidative Stress, Genotoxicity and Vascular Dysfunction in Lean or Obese Zucker Rats
por: Løhr, Mille, et al.
Publicado: (2015) -
Assessment of nanomaterial-induced hepatotoxicity using a 3D human primary multi-cellular microtissue exposed repeatedly over 21 days - the suitability of the in vitro system as an in vivo surrogate
por: Kermanizadeh, Ali, et al.
Publicado: (2019) -
An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials
por: Kermanizadeh, Ali, et al.
Publicado: (2012) -
The importance of inter-individual Kupffer cell variability in the governance of hepatic toxicity in a 3D primary human liver microtissue model
por: Kermanizadeh, Ali, et al.
Publicado: (2019)