NT-PGC-1α Activation Attenuates High-Fat Diet–Induced Obesity by Enhancing Brown Fat Thermogenesis and Adipose Tissue Oxidative Metabolism

The transcriptional coactivator peroxisome proliferator–activated receptor γ coactivator (PGC)-1α and its splice variant N terminal (NT)-PGC-1α regulate adaptive thermogenesis by transcriptional induction of thermogenic and mitochondrial genes involved in energy metabolism. We previously reported th...

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Detalles Bibliográficos
Autores principales: Jun, Hee-Jin, Joshi, Yagini, Patil, Yuvraj, Noland, Robert C., Chang, Ji Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207386/
https://www.ncbi.nlm.nih.gov/pubmed/24848065
http://dx.doi.org/10.2337/db13-1837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207386/
https://www.ncbi.nlm.nih.gov/pubmed/24848065
http://dx.doi.org/10.2337/db13-1837

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