Clicked Cinnamic/Caffeic Esters and Amides as Radical Scavengers and 5-Lipoxygenase Inhibitors

5-Lipoxygenase (5-LO) is the key enzyme responsible for the conversion of arachidonic acid to leukotrienes, a class of lipid mediators implicated in inflammatory disorders. In this paper, we describe the design, synthesis, and preliminary activity studies of novel clicked caffeic esters and amides a...

Descripción completa

Detalles Bibliográficos
Autores principales: Doiron, Jérémie A., Métayer, Benoît, Richard, Ryan R., Desjardins, Dany, Boudreau, Luc H., Levesque, Natalie A., Jean-François, Jacques, Poirier, Samuel J., Surette, Marc E., Touaibia, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207410/
https://www.ncbi.nlm.nih.gov/pubmed/25383225
http://dx.doi.org/10.1155/2014/931756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207410/
https://www.ncbi.nlm.nih.gov/pubmed/25383225
http://dx.doi.org/10.1155/2014/931756

Ejemplares similares