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Syntheses and In Vitro Biological Activity of Some Derivatives of C-9154 Antibiotic

In our continued attempts at designing new antibiotics based on the structure of the C-9154 antibiotic, to simultaneously improve activity and lower toxicity, an analogue to the C-9154 antibiotic and six derivatives of this analogue were synthesized. The approach was to significantly reduce the pola...

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Detalles Bibliográficos
Autores principales: Bello, Isaac Asusheyi, Ndukwe, George Iloegbulam, Amupitan, Joseph Olorunju, Ayo, Rachael Gbekele, Shode, Francis Oluwole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207411/
https://www.ncbi.nlm.nih.gov/pubmed/25374687
http://dx.doi.org/10.1155/2012/782058