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Circular RNAs are depleted of polymorphisms at microRNA binding sites

Motivation: Circular RNAs (circRNAs) are an abundant class of highly stable RNAs that can affect gene regulation by binding and preventing microRNAs (miRNAs) from regulating their messenger RNA (mRNA) targets. Mammals have thousands of circRNAs with predicted miRNA binding sites, but only two circRN...

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Detalles Bibliográficos
Autores principales: Thomas, Laurent F., Sætrom, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207428/
https://www.ncbi.nlm.nih.gov/pubmed/24764460
http://dx.doi.org/10.1093/bioinformatics/btu257