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Circular RNAs are depleted of polymorphisms at microRNA binding sites
Motivation: Circular RNAs (circRNAs) are an abundant class of highly stable RNAs that can affect gene regulation by binding and preventing microRNAs (miRNAs) from regulating their messenger RNA (mRNA) targets. Mammals have thousands of circRNAs with predicted miRNA binding sites, but only two circRN...
Autores principales: | Thomas, Laurent F., Sætrom, Pål |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207428/ https://www.ncbi.nlm.nih.gov/pubmed/24764460 http://dx.doi.org/10.1093/bioinformatics/btu257 |
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