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Aurones: A Promising Heterocyclic Scaffold for the Development of Potent Antileishmanial Agents

A series of (Z)-2-benzylidenebenzofuran-3-(2H)-ones (aurones) bearing a variety of substituents on rings A and B were synthesized and evaluated for their antiparasitic activity against the intracellular amastigote form of Leishmania infantum and their cytotoxicity against human THP1-differentiated m...

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Detalles Bibliográficos
Autores principales: Roussaki, Marina, Costa Lima, Sofia, Kypreou, Anna-Maria, Kefalas, Panagiotis, Cordeiro da Silva, Anabela, Detsi, Anastasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207450/
https://www.ncbi.nlm.nih.gov/pubmed/25374683
http://dx.doi.org/10.1155/2012/196921