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Chromatin Loops as Allosteric Modulators of Enhancer-Promoter Interactions
The classic model of eukaryotic gene expression requires direct spatial contact between a distal enhancer and a proximal promoter. Recent Chromosome Conformation Capture (3C) studies show that enhancers and promoters are embedded in a complex network of looping interactions. Here we use a polymer mo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207457/ https://www.ncbi.nlm.nih.gov/pubmed/25340767 http://dx.doi.org/10.1371/journal.pcbi.1003867 |