Systematic Dissection of Coding Exons at Single Nucleotide Resolution Supports an Additional Role in Cell-Specific Transcriptional Regulation

In addition to their protein coding function, exons can also serve as transcriptional enhancers. Mutations in these exonic-enhancers (eExons) could alter both protein function and transcription. However, the functional consequence of eExon mutations is not well known. Here, using massively parallel...

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Detalles Bibliográficos
Autores principales: Birnbaum, Ramon Y., Patwardhan, Rupali P., Kim, Mee J., Findlay, Gregory M., Martin, Beth, Zhao, Jingjing, Bell, Robert J. A., Smith, Robin P., Ku, Angel A., Shendure, Jay, Ahituv, Nadav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207465/
https://www.ncbi.nlm.nih.gov/pubmed/25340400
http://dx.doi.org/10.1371/journal.pgen.1004592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207465/
https://www.ncbi.nlm.nih.gov/pubmed/25340400
http://dx.doi.org/10.1371/journal.pgen.1004592

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