Structural Insights into Carbonic Anhydrase IX Isoform Specificity of Carbohydrate-Based Sulfamates

[Image: see text] Carbonic anhydrase IX (CA IX) is an extracellular transmembrane homodimeric zinc metalloenzyme that has been validated as a prognostic marker and therapeutic target for several types of aggressive cancers. CA IX shares a close homology with other CA isoforms, making the design of C...

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Detalles Bibliográficos
Autores principales: Moeker, Janina, Mahon, Brian P., Bornaghi, Laurent F., Vullo, Daniela, Supuran, Claudiu T., McKenna, Robert, Poulsen, Sally-Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207533/
https://www.ncbi.nlm.nih.gov/pubmed/25254302
http://dx.doi.org/10.1021/jm5012935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207533/
https://www.ncbi.nlm.nih.gov/pubmed/25254302
http://dx.doi.org/10.1021/jm5012935

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