HIPPO Pathway Members Restrict SOX2 to the Inner Cell Mass Where It Promotes ICM Fates in the Mouse Blastocyst

Pluripotent epiblast (EPI) cells, present in the inner cell mass (ICM) of the mouse blastocyst, are progenitors of both embryonic stem (ES) cells and the fetus. Discovering how pluripotency genes regulate cell fate decisions in the blastocyst provides a valuable way to understand how pluripotency is...

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Detalles Bibliográficos
Autores principales: Wicklow, Eryn, Blij, Stephanie, Frum, Tristan, Hirate, Yoshikazu, Lang, Richard A., Sasaki, Hiroshi, Ralston, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207610/
https://www.ncbi.nlm.nih.gov/pubmed/25340657
http://dx.doi.org/10.1371/journal.pgen.1004618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207610/
https://www.ncbi.nlm.nih.gov/pubmed/25340657
http://dx.doi.org/10.1371/journal.pgen.1004618

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