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Licensing of Yeast Centrosome Duplication Requires Phosphoregulation of Sfi1

Duplication of centrosomes once per cell cycle is essential for bipolar spindle formation and genome maintenance and is controlled in part by cyclin-dependent kinases (Cdks). Our study identifies Sfi1, a conserved component of centrosomes, as the first Cdk substrate required to restrict centrosome d...

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Detalles Bibliográficos
Autores principales: Avena, Jennifer S., Burns, Shannon, Yu, Zulin, Ebmeier, Christopher C., Old, William M., Jaspersen, Sue L., Winey, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207612/
https://www.ncbi.nlm.nih.gov/pubmed/25340401
http://dx.doi.org/10.1371/journal.pgen.1004666