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FHIT Suppresses Epithelial-Mesenchymal Transition (EMT) and Metastasis in Lung Cancer through Modulation of MicroRNAs

Metastasis is the principal cause of cancer death and occurs through multiple, complex processes that involve the concerted action of many genes. A number of studies have indicated that the Fragile Histidine Triad (FHIT) gene product, FHIT, functions as a tumor suppressor in a variety of common huma...

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Detalles Bibliográficos
Autores principales: Suh, Sung-Suk, Yoo, Ji Young, Cui, Ri, Kaur, Balveen, Huebner, Kay, Lee, Taek-Kyun, Aqeilan, Rami I., Croce, Carlo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207614/
https://www.ncbi.nlm.nih.gov/pubmed/25340791
http://dx.doi.org/10.1371/journal.pgen.1004652