Cargando…
FHIT Suppresses Epithelial-Mesenchymal Transition (EMT) and Metastasis in Lung Cancer through Modulation of MicroRNAs
Metastasis is the principal cause of cancer death and occurs through multiple, complex processes that involve the concerted action of many genes. A number of studies have indicated that the Fragile Histidine Triad (FHIT) gene product, FHIT, functions as a tumor suppressor in a variety of common huma...
Autores principales: | Suh, Sung-Suk, Yoo, Ji Young, Cui, Ri, Kaur, Balveen, Huebner, Kay, Lee, Taek-Kyun, Aqeilan, Rami I., Croce, Carlo M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207614/ https://www.ncbi.nlm.nih.gov/pubmed/25340791 http://dx.doi.org/10.1371/journal.pgen.1004652 |
Ejemplares similares
-
Fhit–Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells
por: Druck, Teresa, et al.
Publicado: (2019) -
Impact of FHIT loss on the translation of cancer-associated mRNAs
por: Kiss, Daniel L., et al.
Publicado: (2017) -
Cancer and the FRA3B/FHIT fragile locus: it's a HIT
por: Huebner, K, et al.
Publicado: (2003) -
Restored expression of Fhit protein in Fhit-minus breast cancer cells
por: Campiglio, M, et al.
Publicado: (2001) -
The Fhit protein: an opportunity to overcome chemoresistance
por: Gaudio, Eugenio, et al.
Publicado: (2016)